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β细胞素抗体
产品名称 | 英文名称 | 货号 |
β细胞素抗体 | Beta cellulin | GOY-01K2342 |
商品属性:
英文名称: Beta cellulin
中文名:β细胞素抗体
别 名;Beta cellulin; Beta cellulin precursor; BTC; BTC_HUMAN; OTTHUMP00000160600; OTTHUMP00000219057; Probetacellulin.
研究领域;细胞生物 信号转导 生长因子和激素 淋巴细胞 b-淋巴细胞
抗体来源;Rabbit
克隆类型;Polyclonal
交叉反应;(predicted: Human, )
产品应用;WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量;9/17kDa
细胞定位;细胞膜 细胞外基质 分泌型蛋白
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH conjugated synthetic peptide derived from human Betacellulin: 1-100/178 <Extracellular>
亚 型;IgG
纯化方法;affinity purified by Protein A
缓 冲 液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍:
Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesized as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine signaling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumor growth progression. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors. |
多克隆抗体制备:
完美体育平台合成抗原,保证阳性血清和抗体ELISA效价达到1:32000,由蛋白抗原制备的多抗,保证WB检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,完美体育平台将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体ELISA阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。完美体育平台已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
完美体育平台也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如FITC,HRP等的标记)、以及ELISA,WB,IHC,DB等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是完美体育平台针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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