BCL6B抗体

简要描述：BCL6B抗体免疫原；KLH conjugated synthetic peptide derived from human BCL6B: 141-440/479

产品型号：GOY-01K0704
厂商性质：科研
更新时间：2023-10-24 00:00:00
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BCL6B抗体

产品名称	英文名称	货号
BCL6B抗体	BCL6B	GOY-01K0704

商品属性：

英文名称: BCL6B

中文名:BCL6B抗体

别名；B cell CLL/lymphoma 6, member B (zinc finger protein); B-cell CLL/lymphoma 6, member B (zinc finger protein); BAZF; Bcl6 associated zinc finger protein; Bcl6-associated zinc finger protein; ZBTB28; Zinc finger protein 62; ZNF62; BCL6B_HUMAN.

研究领域；肿瘤干细胞转录调节因子淋巴细胞 b-淋巴细胞锌指蛋白表观遗传学

抗体来源；Rabbit

克隆类型；Polyclonal

交叉反应；(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, )

产品应用；ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量；51kDa

细胞定位；细胞核

性状；Liquid

浓度；1mg/ml

免疫原；KLH conjugated synthetic peptide derived from human BCL6B: 141-440/479

亚型；IgG

纯化方法；affinity purified by Protein A

缓冲液；0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件；Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍:

Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NFⅹB expression, thereby inhibiting NFⅹB-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.

Function:

BCL6B acts as a sequence-specific transcriptional repressor in association with BCL6. It may function in a narrow stage or be related to some events in the early B-cell development.

多克隆抗体制备：

完美体育平台合成抗原，保证阳性血清和抗体ELISA效价达到1：32000，由蛋白抗原制备的多抗，保证WB检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。

鼠单克隆抗体制备:

客户可根据项目实际需求情况灵活选择进行，完美体育平台将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体ELISA阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。

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重组抗体表达服务:

重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。完美体育平台已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。

单项免疫学及检测服务:

完美体育平台也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如FITC，HRP等的标记）、以及ELISA，WB，IHC，DB等检测服务。

抗体定制服务:

已注册商标，主要用于抗体药物发现和开发，是完美体育平台针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。

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