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凋亡相关蛋白TGFb信号抗体
产品名称 | 英文名称 | 货号 |
凋亡相关蛋白TGFb信号抗体 | ARTS/SEPT4 | GOY-01K2155 |
商品属性：
英文名称: ARTS/SEPT4
中文名:凋亡相关蛋白TGFb信号抗体
别 名；Apoptosis Related
Protein TGFb Signalling; Apoptosis-related protein in the TGF-beta signaling
pathway; ARTS; bradeion; Bradeion beta; Brain protein H5; CE5B3; CE5B3 beta;
cell division control-related protein 2; cerebral protein 7; H5 antibody
hCDCREL-2; hucep-7; peanut-like 2; Peanut-like protein 2; PNUTL2; SEPT4;
SEPT4_HUMAN; septin 4; Septin-4.
研究领域；细胞生物 细胞凋亡 细胞周期蛋白
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep, )
产品应用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；55kDa
细胞定位；细胞核 细胞浆
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human ARTS: 91-150/478
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产品介绍:
This gene is a member of the septin family of
nucleotidebinding proteins, originally described in yeast as cell divisioncycle
regulatory proteins. Septins are highly conserved in yeast,Drosophila, and
mouse, and appear to regulate cytoskeletalorganization. Disruption of septin
function disturbs cytokinesisand results in large multinucleate or polyploid
cells. This gene ishighly expressed in brain and heart. Alternatively
splicedtranscript variants encoding different isoforms have been describedfor
this gene. One of the isoforms (known as ARTS) is distinct; itis localized to
the mitochondria, and has a role in apoptosis andcancer. [provided by RefSeq,
Nov 2010]. Aminopeptidase that plays a central role in
peptide trimming, a step required for the generation of most HLA class
I-binding peptides. Peptide trimming is essential to customize longer
precursor peptides to fit them to the correct length required for
presentation on MHC class I molecules. Strongly prefers substrates 9-16
residues long. Rapidly degrades 13-mer to a 9-mer and then stops.
Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic
C-terminus, while it has weak activity toward peptides with charged
C-terminus. May play a role in the inactivation of peptide hormones. May be
involved in the regulation of blood pressure through the inactivation of
angiotensin II and/or the generation of bradykinin in the kidney. |
多克隆抗体制备：
完美体育平台合成抗原，保证阳性血清和抗体ELISA效价达到1：32000，由蛋白抗原制备的多抗，保证WB检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，完美体育平台将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体ELISA阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。完美体育平台已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
完美体育平台也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如FITC，HRP等的标记）、以及ELISA，WB，IHC，DB等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是完美体育平台针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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