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三磷酸腺苷酶家族蛋白3A抗体
产品名称 | 英文名称 | 货号 |
三磷酸腺苷酶家族蛋白3A抗体 | ATAD3A | GOY-01K1035 |
商品属性:
英文名称: ATAD3A
中文名:三磷酸腺苷酶家族蛋白3A抗体
别 名;ATD3A_HUMAN;
ATPase family AAA domain-containing protein 3A;
研究领域;细胞生物 免疫学
抗体来源;Rabbit
克隆类型;Polyclonal
交叉反应;Mouse,
Rat, (predicted: Human, Pig, Cow, Sheep,
)
产品应用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量;71kDa
检测分子量65-71 kDa
细胞定位;细胞浆 细胞膜
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human ATAD3A: 351-450/634
亚 型;IgG
纯化方法;affinity
purified by Protein A
缓 冲 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
产品介绍:
The AAA ATPase family of molecular chaperones are
characterized by a highly conserved AAA motif. Composed of 200-250 residues,
the AAA domain contains Walker homology sequences and imparts ATPase activity.
Members of the AAA ATPase family act as DNA helicases as well as
transcription factors and are thought to be involved in several cellular
functions such as cell-cycle regulation, protein proteolysis, organelle
biogenesis and vesicle-mediated protein transport. Mitochondrial membrane
proteins ATAD3A and ATAD3B contribute to the stabilization of nucleoids which
are large mitochondrial DNA (mtDNA)-protein complexes. ATAD3A/B may
participate in the transformation pathway and the chemosensitivity of oligodendrogliomas.
The genes encoding ATAD3A/B/C maps to human chromosome 1, which houses over
3,000 genes and is the largest human chromosome spanning about 260 million
base pairs and making up 8% of the human genome. Function: Essential for mitochondrial network organization,
mitochondrial metabolism and cell growth at organism and cellular level. May
play an important in mitochondrial protein synthesis. May also participate in
mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and
contribute to nucleoid stability. Required for enhanced channeling of
cholesterol for hormone-dependent steroidogenesis. |
多克隆抗体制备:
完美体育平台合成抗原,保证阳性血清和抗体ELISA效价达到1:32000,由蛋白抗原制备的多抗,保证WB检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,完美体育平台将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体ELISA阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。完美体育平台已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
完美体育平台也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如FITC,HRP等的标记)、以及ELISA,WB,IHC,DB等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是完美体育平台针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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