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前梯度同源蛋白2抗体
产品名称 | 英文名称 | 货号 |
前梯度同源蛋白2抗体 | Anterior Gradient 2 | GOY-01K0190 |
商品属性:
英文名称: Anterior Gradient 2
中文名:前梯度同源蛋白2抗体
别 名;HAG2; AG2
protein; hAG2; Secreted cement gland protein XAG2 homolog; AG 2; AG 2 protein;
AG-2; AG2; AG2 protein; AGR 2; AGR2; AGR2_HUMAN; Anterior gradient 2 homolog
(Xenopus laevis); anterior gradient 2 homolog; Anterior gradient protein 2
homolog; GOB 4; GOB4; HAG 2; hAG-2; hAG2; HAG2/R; HPC 8; HPC8; secreted cement
gland homolog; Secreted cement gland protein XAG 2 homolog; Secreted cement
gland protein XAG-2 homolog; Secreted cement gland protein XAG2 homolog; XAG 2;
XAG2.
研究领域;肿瘤 细胞生物 免疫学 转录调节因子
抗体来源;Rabbit
克隆类型;Polyclonal
交叉反应;(predicted:
Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, )
产品应用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量;20kDa
细胞定位;细胞浆 分泌型蛋白
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human Anterior Gradient 2: 51-150/175
亚 型;IgG
纯化方法;affinity
purified by Protein A
缓 冲 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产品介绍:
AGR2 is a member of the anterior gradient homolog
family. It is the human ortholog of XAG-2, the secreted Xenopus laevis
Anterior Gradient protein. In X. laevis, it is involved in cement gland
differentiation and neural marker gene expression. AGR2 is a secretory
protein encoded by two different AGR2 transcripts. It interacts with LYPD3
and ?dystroglycan (DAG-1). AGR2 is ubiquitously expressed with up-regulated
expression in prostate cancer, breast cancer, lung cancer, renal carcinomas
and endometrial carcinomas. AGR2 expression is positively correlated with
that of the estrogen receptor (ER) and is negatively correlated with that of
the epidermal growth factor receptor (EGFR). AGR2 may serve as a potential
therapeutic marker for various cancers. Required for MUC2 post-transcriptional synthesis
and secretion. May play a role in the production of mucus by intestinal cells
(By similarity). Proto-oncogene that may play a role in cell migration, cell
differentiation and cell growth. |
多克隆抗体制备:
完美体育平台合成抗原,保证阳性血清和抗体ELISA效价达到1:32000,由蛋白抗原制备的多抗,保证WB检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,完美体育平台将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体ELISA阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。完美体育平台已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
完美体育平台也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如FITC,HRP等的标记)、以及ELISA,WB,IHC,DB等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是完美体育平台针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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