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转录激活蛋白2α/TFAP2α/AP-2α抗体
产品名称 | 英文名称 | 货号 |
转录激活蛋白2α/TFAP2α/AP-2α抗体 | AP2 alpha | GOY-01K0130 |
商品属性：
英文名称: AP2 alpha
中文名:转录激活蛋白2α/TFAP2α/AP-2α抗体
别 名；Activating
enhancer binding protein 2 alpha; Activating enhancer-binding protein 2-alpha;
Activator protein 2; AP 2; AP 2 transcription factor; AP 2alpha; AP-2; AP-2
transcription factor; AP2; AP2 Transcription Factor; AP2-alpha; AP2A_HUMAN;
AP2TF; BOFS; Clathrin Adaptor Protein Complex; FLJ51761; TFAP 2; TFAP 2A;
TFAP2; TFAP2A; Transcription factor AP 2 alpha (activating enhancer binding
protein 2 alpha); Transcription factor AP 2 alpha; Transcription factor
AP-2-alpha; Transcription factor AP2 alpha.
研究领域；肿瘤 免疫学 信号转导 细胞凋亡 转录调节因子
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；Mouse, (predicted: Human, Rat, Chicken,
Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用；WB=1:500-2000
ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；48kDa
细胞定位；细胞核
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human AP2 alpha
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产品介绍:
The protein encoded by this gene is a transcription
factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein
functions as either a homodimer or as a heterodimer with similar family
members. This protein activates the transcription of some genes while
inhibiting the transcription of others. Defects in this gene are a cause of
branchiooculofacial syndrome (BOFS). Three transcript variants encoding
different isoforms have been found for this gene. Function: Sequence-specific DNA-binding protein that
interacts with inducible viral and cellular enhancer elements to regulate
transcription of selected genes. AP-2 factors bind to the consensus sequence
5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important
biological functions including proper eye, face, body wall, limb and neural
tube development. They also suppress a number of genes including MCAM/MUC18,
C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early
morphogenesis of the lens vesicle. Together with the CITED2 coactivator,
stimulates the PITX2 P1 promoter transcription activation. Associates with
chromatin to the PITX2 P1 promoter region. |
多克隆抗体制备：
完美体育平台合成抗原，保证阳性血清和抗体ELISA效价达到1：32000，由蛋白抗原制备的多抗，保证WB检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，完美体育平台将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体ELISA阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。完美体育平台已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
完美体育平台也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如FITC，HRP等的标记）、以及ELISA，WB，IHC，DB等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是完美体育平台针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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